The roots of INSTRUCT are in the academic world. In 1993, Prof. Martin Fischer founded a working group for computer-based training for undergraduate and continuing medical education at the Ludwig-Maximilians University in Munich. The focus of this interdisciplinary working group was optimizing the learning with authentic cases and how such cases can help healthcare students in decision making. In 1994 the development of the CASUS virtual patient system began with the aim of developing an easy-to-use authoring system for educators and clinicians to create learning cases for their students.
INSTRUCT AG was founded in May 2000. It has gained appraisal for its innovative concept: the Bavarian Ministry of Economics successfully promoted the establishment of INSTRUCT AG within the scope of the “FLUEGGE” program.